RAF Typhoon FGR4s have conducted a mission with French aircraft in a coordinated attack against an subterranean weapons facility in Syria used by the IS group, according to the UK's MoD.
The facility, located using surveillance, was thought to be containing munitions and bombs, the release indicated, and was situated in hills just above the ancient city of Palmyra in central Syria.
"The RAF jets utilized precision-guided Paveway IV munitions to hit a series of access tunnels leading to the facility... early reports suggest the strike was effective," the MoD said.
There was no sign of any civilian impact in the strike conducted Saturday night and every plane involved made a safe return, the defence officials confirmed.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as the so-called Islamic State - imposed extremist governance over parts of Syria and Iraq until 2019.
"This strike demonstrates British leadership, and resolve to stand shoulder to shoulder with allied nations, to eradicate any re-emergence of IS and their violent and radical beliefs in the Middle East," UK Defence Secretary the Defence Secretary stated.
UK warplanes have performed patrols over Syrian airspace to "forestall any attempted comeback" of Islamic State following its defeat at the climactic battle in Baghuz in the year 2019, the authorities noted.
"I want to thank the personnel of our armed forces participating in this strike for their professionalism and their courage," the Defence Secretary commented. "They were part of numerous British personnel stationed over Christmas and New Year. This operation, to take out dangerous terrorists who pose a risk to our safety, demonstrates how British military are ready to step up, all year round, keeping Britain secure within its borders and influential overseas."
Last December, the United States armed forces executed what it described as a "major assault" on Islamic State objectives in the country, after an assault killed two American soldiers and a civilian linguist in the Palmyra area.
The UN reports Islamic State still boasts roughly 5-7 thousand combatants in both countries.